Obeticholic acid e fa'aaogaina na'o ia pe fa'atasi fo'i togafitiga mo se ma'i ate (primary biliary cholangitis-PBC).
Igoa Oloa | Obeticholic Acid |
Igoa Kemisi | 6-Ethylchenodeoxycholic acid |
Isi Suafa | 3A, 7A -DIHYDROXY-6A -ETIL-5B-CHOLAN-24-OIC ACID;Obeticholic acid 6-ECDCA;6alpha-Ethyl-chenodeoxycholic acid;6-Ecdca;6-Ethylchenodeoxycholic acid;6alph;Obeticholic Acid;6alph;Obeticholic Acid -ECDCA) |
Numera CAS | 459789-99-2 |
Fuafua mole | C26H44O4 |
Fuafua mamafa | 420.63 |
Fa'aaliga | Pa'epa'e pa'epa'e |
Su'ega | 99.0% min |
Malosi | 1.091 g/cm3 |
Lisi Lisi | 108-110 °C |
Fa'apuna | 562.9±25.0 °C |
afifi | 20kg / taga / paʻu, 25kg / taga / paʻu, poʻo pei ona e manaʻomia |
Teuina | Teu le atigipusa tapuni mau i se nofoaga mago & malulu.Aua ne'i tu'u sa'o ile la. |
COA & MSDS | Avanoa |
Obeticholic acid o se dihydroxy-5beta-cholanic acid o le chenodeoxycholic acid o loʻo tauaveina se faʻaopoopoga o le ethyl i le tulaga 6alpha.Ose acid bile semi-synthetic lea e galue e pei o le farnesoid X receptor agonist ma e faʻaaogaina mo togafitiga ole cholangitis muamua.E iai sona sao o se faʻamaʻi faʻamaʻi faʻamaʻi X farnesoid ma se sui o le hepatoprotective.O le dihydroxy-5beta-cholanic acid, o le 3alpha-hydroxy steroid ma le 7alpha-hydroxy steroid.E maua mai le chenodeoxycholic acid.
Obeticholic acid (OCA) ose vaila'au fa'afo'i fa'afoliga fa'afoliga ma le malosi malosi o le fa'ama'i faaniukilia farnesoid X (FXR) lea e fa'aaogaina e togafitia ai fa'ama'i ate e aofia ai le cholangitis muamua.
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Taimi muamua
≤100kg: i totonu o le tolu aso faigaluega talu ona maua le totogi.
>100kg: tasi le vaiaso
Fa'ata'ita'iga
Avanoa.
afifi
20kg / taga / pa'u, 25kg / taga / pa'u
pe pei ona e manaʻomia.
Teuina
Teu le atigipusa tapuni mau i se nofoaga mago & malulu.
Aua ne'i tu'u sa'o ile la.